Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice
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چکیده
منابع مشابه
Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice.
Estrogen depletion in postmenopausal women is a significant risk factor for the development of Alzheimer's disease (AD), and estrogen-based hormone therapy may reduce this risk. However, the effects of progesterone both alone and in combination with estrogen on AD neuropathology remain unknown. In this study, we used the triple transgenic mouse model of AD (3xTg-AD) to investigate the individua...
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ژورنال
عنوان ژورنال: Molecular Neurobiology
سال: 2013
ISSN: 0893-7648,1559-1182
DOI: 10.1007/s12035-013-8539-y